deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT02991196

Antibody DS-8273a Administered in Combination With Nivolumab in Subjects With Advanced Colorectal Cancer

A Phase 1 Study of TRAIL-R2 (DR5) Antibody DS-8273a Administered in Combination With Nivolumab in Subjects With Advanced Colorectal Cancer

Sponsor: Bristol-Myers Squibb

Updated 14 times since 2017 Last updated: Feb 8, 2019 Started: Dec 1, 2016 Primary completion: Sep 22, 2017 Completion: Sep 22, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business Decision

A PHASE1 clinical study on Colorectal Neoplasm, this trial is terminated or withdrawn. The trial is conducted by Bristol-Myers Squibb and has accumulated 14 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Aug 2017 · 4 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Jan 2021 · 22 months · monthly snapshot~Jan 2021 – ~Mar 2024 · 38 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Mar 2024 — Jul 2024 [monthly]

    Terminated PHASE1

  5. Jan 2021 — Mar 2024 [monthly]

    Terminated PHASE1

Show 9 earlier versions
  1. Mar 2019 — Jan 2021 [monthly]

    Terminated PHASE1

  2. Jan 2019 — Mar 2019 [monthly]

    Terminated PHASE1

  3. Jun 2018 — Jan 2019 [monthly]

    Terminated PHASE1

  4. Oct 2017 — Jun 2018 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  5. Sep 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE1

  6. Aug 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  7. Apr 2017 — Aug 2017 [monthly]

    Recruiting PHASE1

  8. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE1

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Dec 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
  • Daiichi Sankyo
Data source: Daiichi Sankyo

For direct contact, visit the study record on ClinicalTrials.gov .