Efficacy of Three Experimental Toothpastes to Remove Plaque
Dose Response of Three Experimental Dentifrices in Plaque Removal in a Single Brushing Model
Sponsor: GlaxoSmithKline
Listed as NCT02992691, this NA trial focuses on Dental Plaque and remains completed. Sponsored by GlaxoSmithKline, it has been updated 10 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Study Description(click to expand)This will be a single centre, controlled, examiner blind, five treatment, five period, crossover design study in healthy participants. This study will evaluate the dose response of three experimental toothpastes (test product 1, test product 2 and test product 3) to remove plaque after a single brushing, compared to a positive control and negative control dentifrice. Plaque removal efficacy will be measured by Turesky modification of Quigley Hein Plaque Index (TPI).
This will be a single centre, controlled, examiner blind, five treatment, five period, crossover design study in healthy participants. This study will evaluate the dose response of three experimental toothpastes (test product 1, test product 2 and test product 3) to remove plaque after a single brushing, compared to a positive control and negative control dentifrice. Plaque removal efficacy will be measured by Turesky modification of Quigley Hein Plaque Index (TPI).
Status Flow
Change History
10 versions recorded-
Jan 2026 — Present [monthly]
Completed NA
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Sep 2024 — Present [monthly]
Completed NA
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Jul 2024 — Sep 2024 [monthly]
Completed NA
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Jan 2021 — Jul 2024 [monthly]
Completed NA
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Jun 2019 — Jan 2021 [monthly]
Completed NA
▶ Show 5 earlier versions
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Mar 2019 — Jun 2019 [monthly]
Completed NA
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Nov 2018 — Mar 2019 [monthly]
Completed NA
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Jun 2018 — Nov 2018 [monthly]
Completed NA
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May 2017 — Jun 2018 [monthly]
Completed NA
Status: Not Yet Recruiting → Completed
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Jan 2017 — May 2017 [monthly]
Not Yet Recruiting NA
First recorded
Dec 2016
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- GlaxoSmithKline
For direct contact, visit the study record on ClinicalTrials.gov .