deltatrials
Active Not Recruiting PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT02997878

Selected Mesenchymal Stromal Cells to Reduce Inflammation in Patients With PSC and AIH (Merlin)

An Adaptive, Multicentre, Phase IIa, Multi-disease Trial Investigating the Safety & Activity of a Single Infusion of Selected Mesenchymal Stromal Cells in the Treatment of Patients With Primary Sclerosing Cholangitis & Autoimmune Hepatitis

Sponsor: NHS Blood and Transplant

Interventions Orbcel-C
Updated 13 times since 2017 Last updated: Jul 10, 2024 Started: Dec 7, 2018 Primary completion: Nov 23, 2023 Completion: Oct 1, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02997878, this PHASE1/PHASE2 trial focuses on Cholangitis, Sclerosing and Hepatitis, Autoimmune and remains ongoing. Sponsored by NHS Blood and Transplant, it has been updated 13 times since 2018, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Dec 2018 · 5 months · monthly snapshot~Dec 2018 – ~Mar 2019 · 3 months · monthly snapshot~Mar 2019 – ~Jan 2021 · 22 months · monthly snapshot~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshot~Mar 2022 – ~Dec 2022 · 9 months · monthly snapshot~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2024 — Present [monthly]

    Active Not Recruiting PHASE1/PHASE2

  2. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Status: RecruitingActive Not Recruiting

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Dec 2022 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Unknown StatusRecruiting

  5. Mar 2022 — Dec 2022 [monthly]

    Unknown Status PHASE1_PHASE2

    Status: RecruitingUnknown Status

Show 8 earlier versions
  1. Jan 2021 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

  2. Mar 2019 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Dec 2018 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  4. Jul 2018 — Dec 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  5. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  6. Jun 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  7. Feb 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • NHS Blood and Transplant
  • University of Birmingham
Data source: University of Birmingham

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations