deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03000439

A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF TOFACITINIB FOR TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS (SJIA) WITH ACTIVE SYSTEMIC FEATURES IN CHILDREN AND ADOLESCENT SUBJECTS

Sponsor: Pfizer

Conditions Arthritis Juvenile Idiopathic
Interventions In double-blind phase: treatment with tofacitinib or placebo in 1:1 ratio In open-label phase: treatment with tofacitinib
Updated 68 times since 2017 Last updated: May 30, 2025 Started: May 10, 2018 Primary completion: Mar 27, 2024 Completion: Mar 27, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Arthritis Juvenile Idiopathic, this trial is completed. The trial is conducted by Pfizer and has accumulated 68 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jun 2017 · 2 months · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

68 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Jun 2025 — Sep 2025 [monthly]

    Completed PHASE3

  3. Sep 2024 — Jun 2025 [monthly]

    Completed PHASE3

  4. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE3

  5. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE3

▶ Show 63 earlier versions

  1. May 2024 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  2. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Dec 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

  6. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  7. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE3

  8. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  9. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  10. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  11. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  12. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

  13. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  14. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  15. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  16. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE3

  17. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  18. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  19. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  20. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  21. May 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  22. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  23. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  24. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  25. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  26. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  27. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  28. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  29. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  30. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  31. Apr 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  32. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  33. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  34. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  35. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  36. Aug 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  37. May 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  38. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE3

  39. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  40. Jan 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  41. Oct 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  42. Aug 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  43. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  44. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  45. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  46. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  47. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  48. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE3

  49. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  50. Sep 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  51. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  52. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  53. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  54. May 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE3

  55. Mar 2018 — May 2018 [monthly]

    Not Yet Recruiting PHASE3

  56. Jan 2018 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE3

  57. Dec 2017 — Jan 2018 [monthly]

    Not Yet Recruiting PHASE3

  58. Oct 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE3

  59. Aug 2017 — Oct 2017 [monthly]

    Not Yet Recruiting PHASE3

  60. Jun 2017 — Aug 2017 [monthly]

    Not Yet Recruiting PHASE3

  61. Apr 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE3

  62. Feb 2017 — Apr 2017 [monthly]

    Not Yet Recruiting PHASE3

  63. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ankara, Turkey (Türkiye) , Beijing, China , Botucatu, Brazil , Budapest, Hungary , Calgary, Canada , Cape Town, South Africa , Changsha, China , Chengdu, China , Chicago, United States , Chongqing, China and 38 more locations