deltatrials
Terminated NA INTERVENTIONAL 3-arm NCT03016975

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE) (ACTIVE)

Annular ReduCtion for Transcatheter Treatment of Insufficient Mitral ValvE (ACTIVE): A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Assess Transcatheter Mitral Valve Repair With Edwards Cardioband System and GDMT vs GDMT Alone in Patients With FMR and Heart Failure

Sponsor: Edwards Lifesciences

Updated 26 times since 2017 Last updated: Nov 8, 2023 Started: Jun 1, 2017 Primary completion: Jul 19, 2019 Completion: Sep 20, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Procedure and device development

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A NA clinical study on Functional Mitral Regurgitation and Mitral Insufficiency, this trial is terminated or withdrawn. The trial is conducted by Edwards Lifesciences and has accumulated 26 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Feb 2020 · 10 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Dec 2023 · 10 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

26 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated NA

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated NA

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated NA

  4. Dec 2023 — Jul 2024 [monthly]

    Terminated NA

    Status: Active Not RecruitingTerminated

  5. Feb 2023 — Dec 2023 [monthly]

    Active Not Recruiting NA

Show 21 earlier versions
  1. Dec 2022 — Feb 2023 [monthly]

    Active Not Recruiting NA

  2. Jan 2021 — Dec 2022 [monthly]

    Active Not Recruiting NA

  3. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

  4. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting NA

  5. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting NA

  6. Feb 2020 — May 2020 [monthly]

    Active Not Recruiting NA

  7. Apr 2019 — Feb 2020 [monthly]

    Active Not Recruiting NA

  8. Jan 2019 — Apr 2019 [monthly]

    Active Not Recruiting NA

  9. Dec 2018 — Jan 2019 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  10. Nov 2018 — Dec 2018 [monthly]

    Recruiting NA

  11. Sep 2018 — Nov 2018 [monthly]

    Recruiting NA

  12. Aug 2018 — Sep 2018 [monthly]

    Recruiting NA

  13. Jul 2018 — Aug 2018 [monthly]

    Recruiting NA

  14. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  15. Mar 2018 — Jun 2018 [monthly]

    Recruiting NA

  16. Jan 2018 — Mar 2018 [monthly]

    Recruiting NA

  17. Dec 2017 — Jan 2018 [monthly]

    Recruiting NA

  18. Oct 2017 — Dec 2017 [monthly]

    Recruiting NA

  19. Sep 2017 — Oct 2017 [monthly]

    Recruiting NA

  20. Aug 2017 — Sep 2017 [monthly]

    Recruiting NA

    Status: WithheldRecruiting

  21. Feb 2017 — Aug 2017 [monthly]

    Withheld NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Edwards Lifesciences
Data source: Edwards Lifesciences

For direct contact, visit the study record on ClinicalTrials.gov .