deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT03031626

Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome

Comparison of Therapeutic Oxygen Versus Medical Air for the Treatment of Central Sleep Apnea in Infants and Children With Prader Willi Syndrome: A Proof of Concept Study

Sponsor: The Hospital for Sick Children

Conditions Prader-Willi Syndrome Sleep Apnea, Central
Interventions Medical Air vs Oxygen
Updated 14 times since 2017 Last updated: Jun 4, 2025 Started: Sep 1, 2016 Primary completion: Mar 15, 2025 Completion: Mar 15, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Prader-Willi Syndrome and Sleep Apnea, Central and is currently completed. The Hospital for Sick Children leads this study, which shows 14 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Nov 2019 · 6 months · monthly snapshot~Nov 2019 – ~Jan 2021 · 14 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Nov 2022 · 9 months · monthly snapshot~Nov 2022 – ~Dec 2023 · 13 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Jul 2025 · 8 months · monthly snapshot~Jul 2025 – present · 14 months · monthly snapshot

Change History

14 versions recorded

  1. Jul 2025 — Present [monthly]

    Completed PHASE4

    Status: Recruiting → Completed

  2. Nov 2024 — Jul 2025 [monthly]

    Recruiting PHASE4

  3. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  5. Dec 2023 — Jul 2024 [monthly]

    Recruiting PHASE4

▶ Show 9 earlier versions

  1. Nov 2022 — Dec 2023 [monthly]

    Recruiting PHASE4

  2. Feb 2022 — Nov 2022 [monthly]

    Recruiting PHASE4

  3. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE4

  4. Mar 2021 — Sep 2021 [monthly]

    Recruiting PHASE4

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE4

  6. Nov 2019 — Jan 2021 [monthly]

    Recruiting PHASE4

  7. May 2019 — Nov 2019 [monthly]

    Recruiting PHASE4

  8. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE4

  9. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

    First recorded

Sep 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • The Hospital for Sick Children
Data source: The Hospital for Sick Children

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations