deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03032172

A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy (Jewelfish)

An Open-Label Study to Investigate the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Risdiplam (RO7034067) in Adult and Pediatric Patients With Spinal Muscular Atrophy

Sponsor: Hoffmann-La Roche

Interventions Risdiplam
Updated 49 times since 2017 Last updated: Sep 11, 2025 Started: Mar 3, 2017 Primary completion: Feb 7, 2025 Completion: Feb 7, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Spinal Muscular Atrophy and is currently completed. Hoffmann-La Roche leads this study, which shows 49 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~May 2017 · 2 months · monthly snapshot~May 2017 – ~Aug 2017 · 3 months · monthly snapshot~Aug 2017 – ~Jan 2018 · 5 months · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Jun 2020 · 4 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshot~Nov 2023 – ~Jan 2024 · 2 months · monthly snapshot~Jan 2024 – ~Apr 2024 · 3 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2025 · 3 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

49 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Nov 2025 [monthly]

    Completed PHASE2

  3. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

Show 44 earlier versions
  1. Oct 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE2

  6. Nov 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2

  7. Aug 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2

  8. May 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

  9. Feb 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2

  10. Nov 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  11. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2

  12. Jun 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  13. Mar 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

  14. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

  15. Nov 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  16. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE2

  17. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  18. Mar 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  19. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  20. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  21. Aug 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  22. Jun 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  23. Feb 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  24. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE2

  25. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

  26. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  27. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  28. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  29. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  30. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  31. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  32. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  33. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  34. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  35. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  36. Sep 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  37. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  38. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  39. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  40. Jan 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  41. Aug 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  42. May 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

  43. Mar 2017 — May 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  44. Feb 2017 — Mar 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .