deltatrials
Terminated PHASE3 INTERVENTIONAL 3-arm NCT03053050

Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis (STELLAR-3)

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis

Sponsor: Gilead Sciences

Updated 26 times since 2017 Last updated: Jun 10, 2020 Started: Feb 13, 2017 Primary completion: Jun 19, 2019 Completion: Jun 19, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This study was terminated early due to lack of efficacy based on the results of the Week 48 analysis as prespecified in the clinical study protocol.

A PHASE3 clinical study on Nonalcoholic Steatohepatitis, this trial is terminated or withdrawn. The trial is conducted by Gilead Sciences and has accumulated 26 data snapshots since 2017. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~May 2017 · 30 days · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Jul 2019 · 5 months · monthly snapshot~Jul 2019 – ~Jul 2020 · 12 months · monthly snapshot~Jul 2020 – ~Nov 2020 · 4 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

26 versions recorded
  1. Dec 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2025 — Dec 2025 [monthly]

    Terminated PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  5. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE3

Show 21 earlier versions
  1. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

  2. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  3. Jul 2020 — Nov 2020 [monthly]

    Terminated PHASE3

    Status: CompletedTerminated

  4. Jul 2019 — Jul 2020 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Feb 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE3

  6. Dec 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  7. Jun 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE3

  8. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  9. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE3

  10. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE3

  11. Jan 2018 — Feb 2018 [monthly]

    Recruiting PHASE3

  12. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  13. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  14. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

  15. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  16. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE3

  17. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  18. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE3

  19. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

  20. Apr 2017 — May 2017 [monthly]

    Recruiting PHASE3

  21. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gilead Sciences
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .