deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT03076164

A Phase 1/2 Trial of Trametinib and Erlotinib in Patients With EGFR-Mutant Lung Adenocarcinomas and Acquired Resistance to Erlotinib

Sponsor: GlaxoSmithKline

Updated 13 times since 2017 Last updated: Mar 6, 2024 Started: Mar 1, 2017 Primary completion: Dec 18, 2020 Completion: Dec 18, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Lung Adenocarcinoma and Lung Cancer and is currently completed. GlaxoSmithKline leads this study, which shows 13 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Apr 2017 – ~Jun 2018 · 14 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~May 2019 · 8 months · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Jul 2020 · 11 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshot~Mar 2022 – ~Dec 2022 · 9 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~May 2024 · 16 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 21 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. May 2024 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Jan 2023 — May 2024 [monthly]

    Completed PHASE1_PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE1_PHASE2

Show 8 earlier versions
  1. Mar 2022 — Dec 2022 [monthly]

    Completed PHASE1_PHASE2

  2. Jan 2021 — Mar 2022 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  3. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  4. Aug 2019 — Jul 2020 [monthly]

    Recruiting PHASE1_PHASE2

  5. May 2019 — Aug 2019 [monthly]

    Recruiting PHASE1_PHASE2

  6. Sep 2018 — May 2019 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE1_PHASE2

  8. Apr 2017 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Mar 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
  • Memorial Sloan Kettering Cancer Center
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .