deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT03085004

CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts (CHARM)

CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts: a Prospective, Randomized, Double-blind, Multi-center Clinical Trial

Sponsor: Milton S. Hershey Medical Center

Conditions EUS-FNA Pancreatic Cyst
Interventions Ethanol Normal saline Paclitaxel + Gemcitabine admixture
Updated 20 times since 2017 Last updated: Apr 16, 2025 Started: Apr 12, 2019 Primary completion: Dec 31, 2025 Completion: Feb 1, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03085004, this PHASE3 trial focuses on EUS-FNA and Pancreatic Cyst and remains ongoing. Sponsored by Milton S. Hershey Medical Center, it has been updated 20 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2017 – ~Jun 2018 · 13 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Apr 2019 · 5 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jan 2020 · 7 months · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jan 2022 · 9 months · monthly snapshot~Jan 2022 – ~May 2022 · 4 months · monthly snapshot~May 2022 – ~May 2023 · 12 months · monthly snapshot~May 2023 – ~May 2024 · 12 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~May 2025 · 3 months · monthly snapshot~May 2025 – present · 14 months · monthly snapshot

Change History

20 versions recorded

  1. May 2025 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Feb 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Dec 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 15 earlier versions

  1. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  2. May 2023 — May 2024 [monthly]

    Recruiting PHASE3

  3. May 2022 — May 2023 [monthly]

    Recruiting PHASE3

  4. Jan 2022 — May 2022 [monthly]

    Recruiting PHASE3

  5. Apr 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  6. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  7. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Active Not Recruiting → Recruiting

  8. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  9. Jan 2020 — May 2020 [monthly]

    Recruiting PHASE3

  10. Jun 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  11. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  12. Apr 2019 — May 2019 [monthly]

    Not Yet Recruiting PHASE3

  13. Nov 2018 — Apr 2019 [monthly]

    Not Yet Recruiting PHASE3

  14. Jun 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE3

    Phase: PHASE2_PHASE3 → PHASE3

  15. May 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Milton S. Hershey Medical Center
  • National Cancer Institute (NCI)
Data source: Milton S. Hershey Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations