deltatrials
Completed NA INTERVENTIONAL 2-arm NCT03098706

Therapeutic Hypothermia in Expanded Criteria Brain-dead Donors and Kidney-graft Function (HYPOREME)

Impact of Therapeutic Hypothermia in Expanded Criteria Brain-dead Donors on Kidney-graft Function in the Kidney-transplant Recipients: Multicenter Randomized Controlled Trial HYPOREME

Sponsor: Ministry of Health, France

Conditions Brain Death Critical Illness Hypothermia Kidney Transplant; Complications Organ Donor
Interventions Procedure active Procedure control: normothermia
Updated 15 times since 2017 Last updated: Jun 17, 2022 Started: Nov 8, 2017 Primary completion: Mar 21, 2022 Completion: Mar 21, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Brain Death and Critical Illness and is currently completed. Ministry of Health, France leads this study, which shows 15 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~May 2017 – ~Jun 2018 · 13 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Nov 2019 · 5 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Nov 2020 · 10 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Jul 2022 · 18 months · monthly snapshot~Jul 2022 – ~Jul 2024 · 24 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed NA

  2. Sep 2024 — Sep 2025 [monthly]

    Completed NA

  3. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  4. Jul 2022 — Jul 2024 [monthly]

    Completed NA

    Status: Recruiting → Completed

  5. Jan 2021 — Jul 2022 [monthly]

    Recruiting NA

▶ Show 10 earlier versions

  1. Nov 2020 — Jan 2021 [monthly]

    Recruiting NA

  2. Jan 2020 — Nov 2020 [monthly]

    Recruiting NA

  3. Dec 2019 — Jan 2020 [monthly]

    Recruiting NA

  4. Nov 2019 — Dec 2019 [monthly]

    Recruiting NA

  5. Jun 2019 — Nov 2019 [monthly]

    Recruiting NA

  6. Apr 2019 — Jun 2019 [monthly]

    Recruiting NA

  7. Jan 2019 — Apr 2019 [monthly]

    Recruiting NA

  8. Dec 2018 — Jan 2019 [monthly]

    Recruiting NA

  9. Jun 2018 — Dec 2018 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  10. May 2017 — Jun 2018 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ministry of Health, France
  • Nantes University Hospital
Data source: Nantes University Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amiens, France , Angers, France , Angoulême, France , Avignon, France , Blois, France , Bordeaux, France , Bourges, France , Brest, France , Caen, France , Cholet, France and 40 more locations