deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT03109080

Olaparib & Radiation Therapy for Patients Triple Negative Breast Cancer (TNBC) (RadioPARP)

A Phase I of Olaparib With Radiation Therapy in Patients With Inflammatory, Loco-regionally Advanced or Metastatic TNBC (Triple Negative Breast Cancer) or Patient With Operated TNBC With Residual Disease

Sponsor: AstraZeneca

Updated 15 times since 2017 Last updated: Nov 19, 2025 Started: Jul 24, 2017 Primary completion: Feb 17, 2020 Completion: Nov 29, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Breast Neoplasm Malignant Female and Breast Neoplasms, Triple-Negative and is currently completed. AstraZeneca leads this study, which shows 15 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2017 – ~Jul 2017 · 2 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Nov 2019 · 12 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~Oct 2020 · 7 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshot~Nov 2022 – ~Dec 2023 · 13 months · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2025 · 15 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

15 versions recorded
  1. Dec 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Dec 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Feb 2024 — Jul 2024 [monthly]

    Completed PHASE1

  5. Dec 2023 — Feb 2024 [monthly]

    Completed PHASE1

    Status: Unknown StatusCompleted

Show 10 earlier versions
  1. Nov 2022 — Dec 2023 [monthly]

    Unknown Status PHASE1

    Status: Active Not RecruitingUnknown Status

  2. Jan 2021 — Nov 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE1

  5. Mar 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  6. Nov 2019 — Mar 2020 [monthly]

    Recruiting PHASE1

  7. Nov 2018 — Nov 2019 [monthly]

    Recruiting PHASE1

  8. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  9. Jul 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  10. May 2017 — Jul 2017 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Institut Curie
Data source: Institut Curie

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations