deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03110133

Efficacy, Safety, and Tolerability Study of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Recurrent C. Diff (PRISM3)

A Multicenter, Double-Blind, Parallel-Arm, Placebo-Controlled, Phase 2 Study of the Efficacy, Safety, and Tolerability of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Recurrence of Clostridium Difficile Infection

Sponsor: Finch Research and Development LLC.

Conditions Clostridium Difficile Infection Recurrence
Interventions Full Spectrum Microbiota Placebo
Updated 26 times since 2017 Last updated: Sep 6, 2022 Started: May 8, 2017 Primary completion: Feb 28, 2020 Completion: Jun 18, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Clostridium Difficile Infection Recurrence and is currently completed. Finch Research and Development LLC. leads this study, which shows 26 recorded versions since 2017 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Nov 2017 · 2 months · monthly snapshot~Nov 2017 – ~Jan 2018 · 2 months · monthly snapshot~Jan 2018 – ~May 2018 · 4 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Feb 2020 · 4 months · monthly snapshot~Feb 2020 – ~Jul 2020 · 5 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Sep 2022 · 19 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

26 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

▶ Show 21 earlier versions

  1. Nov 2022 — Dec 2022 [monthly]

    Completed PHASE2

  2. Sep 2022 — Nov 2022 [monthly]

    Completed PHASE2

  3. Feb 2021 — Sep 2022 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  4. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Feb 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  7. Oct 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  8. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  9. Apr 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  10. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  11. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

  12. Sep 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  13. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  14. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  15. Jan 2018 — May 2018 [monthly]

    Recruiting PHASE2

  16. Nov 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  17. Sep 2017 — Nov 2017 [monthly]

    Recruiting PHASE2

  18. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

  19. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

  20. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  21. May 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Finch Research and Development LLC.
Data source: Finch Research and Development LLC.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Annandale, United States , Atlanta, United States , Aurora, United States , Boston, United States , Bridgeport, United States , Burr Ridge, United States , Butte, United States , Calgary, Canada , Chapel Hill, United States , Charlottesville, United States and 44 more locations