deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT03110315

A Study of Suvorexant in Patients With Multiple Sclerosis Fatigue and Insomnia (DREAM)

A Double-blind, Crossover, Placebo-controlled Study to Compare the Effects of Nighttime Administration of Suvorexant in Patients With Multiple Sclerosis Fatigue and Insomnia

Sponsor: Merck Sharp & Dohme LLC

Updated 11 times since 2017 Last updated: Jan 27, 2025 Started: Mar 28, 2017 Primary completion: Mar 21, 2022 Completion: Mar 21, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03110315, this PHASE4 trial focuses on Fatigue and Insomnia and remains completed. Sponsored by Merck Sharp & Dohme LLC, it has been updated 11 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2017 – ~Jun 2018 · 13 months · monthly snapshotRecruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotRecruiting~Jul 2018 – ~May 2019 · 10 months · monthly snapshotRecruiting~May 2019 – ~Jan 2021 · 20 months · monthly snapshotRecruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotRecruiting~May 2021 – ~May 2022 · 12 months · monthly snapshotRecruiting~May 2022 – ~Jun 2022 · 31 days · monthly snapshotCompleted~Jun 2022 – ~Jul 2024 · 25 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotCompleted~Mar 2025 – present · 16 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Mar 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jun 2022 — Jul 2024 [monthly]

    Completed PHASE4

  5. May 2022 — Jun 2022 [monthly]

    Completed PHASE4

    Status: RecruitingCompleted

Show 6 earlier versions
  1. May 2021 — May 2022 [monthly]

    Recruiting PHASE4

  2. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE4

  3. May 2019 — Jan 2021 [monthly]

    Recruiting PHASE4

  4. Jul 2018 — May 2019 [monthly]

    Recruiting PHASE4

  5. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE4

  6. May 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

    First recorded

Mar 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
  • Theodore R. Brown, MD MPH
Data source: EvergreenHealth

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations