deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT03122106

Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

A Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of a Neoantigen DNA Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Sponsor: National Cancer Institute (NCI)

Conditions Cancer of the Pancreas Pancreas Cancer Pancreatic Cancer
Interventions Peripheral blood draws Personalized neoantigen DNA vaccine TDS-IM Electrode Array System
Updated 20 times since 2017 Last updated: Oct 3, 2023 Started: Jan 5, 2018 Primary completion: Sep 3, 2021 Completion: Aug 13, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Loss of funding

Other terminated trials from National Cancer Institute (NCI)

See all terminations from National Cancer Institute (NCI)

Other Cancer of the Pancreas trials with similar outcome

Browse all Cancer of the Pancreas trials

This PHASE1 trial investigates Cancer of the Pancreas and Pancreas Cancer and is currently terminated or withdrawn. National Cancer Institute (NCI) leads this study, which shows 20 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2017 – ~Feb 2018 · 9 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Mar 2019 · 7 months · monthly snapshot~Mar 2019 – ~Oct 2019 · 7 months · monthly snapshot~Oct 2019 – ~Feb 2020 · 4 months · monthly snapshot~Feb 2020 – ~Jun 2020 · 4 months · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~Oct 2021 · 6 months · monthly snapshot~Oct 2021 – ~Nov 2022 · 13 months · monthly snapshot~Nov 2022 – ~Sep 2023 · 10 months · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

20 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Nov 2023 — Jul 2024 [monthly]

    Terminated PHASE1

  5. Sep 2023 — Nov 2023 [monthly]

    Terminated PHASE1

▶ Show 15 earlier versions

  1. Nov 2022 — Sep 2023 [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

  2. Oct 2021 — Nov 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Apr 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Feb 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE1

  5. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1

  6. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  7. Jun 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  8. Feb 2020 — Jun 2020 [monthly]

    Recruiting PHASE1

  9. Oct 2019 — Feb 2020 [monthly]

    Recruiting PHASE1

  10. Mar 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  11. Aug 2018 — Mar 2019 [monthly]

    Recruiting PHASE1

  12. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  13. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  14. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  15. May 2017 — Feb 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Washington University School of Medicine
Data source: Washington University School of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations