deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03128515

Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas (NOHARM-MTD)

Optimizing Hydroxyurea Therapy in Children With Sickle Cell Anemia In Malaria Endemic Areas: The NOHARM Maximum Tolerated Dose (MTD) Study

Sponsor: Children's Hospital Medical Center, Cincinnati

Interventions Hydroxyurea
Updated 9 times since 2017 Last updated: Feb 19, 2020 Started: Jul 26, 2017 Primary completion: Apr 7, 2019 Completion: Jan 28, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Malaria and Sickle Cell Anemia, this trial is completed. The trial is conducted by Children's Hospital Medical Center, Cincinnati and has accumulated 9 data snapshots since 2017. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshotNot Yet Recruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotRecruiting~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotRecruiting~Nov 2018 – ~Sep 2019 · 10 months · monthly snapshotRecruiting~Sep 2019 – ~Mar 2020 · 6 months · monthly snapshotActive Not Recruiting~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  4. Mar 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Sep 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

Show 4 earlier versions
  1. Nov 2018 — Sep 2019 [monthly]

    Recruiting PHASE3

  2. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  3. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  4. Jun 2017 — Oct 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Hospital Medical Center, Cincinnati
  • Doris Duke Charitable Foundation
  • Indiana University
  • Makerere University
  • Mulago Hospital, Uganda
Data source: Indiana University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations