deltatrials
Completed PHASE2 INTERVENTIONAL 6-arm NCT03137069

A Study of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU).

A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Pilot and Dose-Ranging Study of GDC-0853 in Patients With Refractory Chronic Spontaneous Urticaria (CSU).

Sponsor: Genentech, Inc.

Conditions Urticaria
Interventions GDC-0853 Placebo
Updated 28 times since 2017 Last updated: Sep 28, 2020 Started: May 26, 2017 Primary completion: Sep 27, 2019 Completion: Oct 25, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03137069, this PHASE2 trial focuses on Urticaria and remains completed. Sponsored by Genentech, Inc., it has been updated 28 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jun 2017 – ~Jan 2018 · 7 months · monthly snapshot~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jun 2019 · 6 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Oct 2020 · 6 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

28 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE2

▶ Show 23 earlier versions

  1. Oct 2020 — Jan 2021 [monthly]

    Completed PHASE2

  2. Apr 2020 — Oct 2020 [monthly]

    Completed PHASE2

  3. Mar 2020 — Apr 2020 [monthly]

    Completed PHASE2

    Status: Terminated → Completed

  4. Jan 2020 — Mar 2020 [monthly]

    Terminated PHASE2

  5. Dec 2019 — Jan 2020 [monthly]

    Terminated PHASE2

    Status: Recruiting → Terminated

  6. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  7. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  8. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  9. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  10. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  11. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  12. Dec 2018 — Jun 2019 [monthly]

    Recruiting PHASE2

  13. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  14. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  15. Aug 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  16. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  18. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  19. Apr 2018 — May 2018 [monthly]

    Recruiting PHASE2

  20. Mar 2018 — Apr 2018 [monthly]

    Recruiting PHASE2

  21. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  22. Jan 2018 — Feb 2018 [monthly]

    Recruiting PHASE2

  23. Jun 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

    First recorded

May 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Genentech, Inc.
Data source: Genentech, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Augsburg, Germany , Bakersfield, United States , Berlin, Germany , Birmingham, United States , Burlington, United States , Cypress, United States , Dresden, Germany , Drummondville, Canada , East Providence, United States , Hamilton, Canada and 17 more locations