deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 5-arm NCT03138096

Safety and Protective Efficacy of Pb(PfCS@UIS4) (PbVac)

Safety and Protective Efficacy of Genetically Modified Plasmodium Berghei (Pb(PfCS@UIS4)) Malaria Parasites in Healthy Volunteers

Sponsor: Erasmus Medical Center

Updated 12 times since 2017 Last updated: Feb 23, 2022 Started: May 29, 2017 Primary completion: Mar 28, 2018 Completion: Oct 3, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Controlled Human Malaria Infection (CHMI) and Malaria,Falciparum and is currently completed. Erasmus Medical Center leads this study, which shows 12 recorded versions since 2017 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshotRecruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshotActive Not Recruiting~Dec 2018 – ~Jan 2021 · 25 months · monthly snapshotCompleted~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshotCompleted~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshotCompleted~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshotCompleted~Apr 2022 – ~Dec 2022 · 8 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE1_PHASE2

  5. Apr 2022 — Dec 2022 [monthly]

    Completed PHASE1_PHASE2

Show 7 earlier versions
  1. Mar 2022 — Apr 2022 [monthly]

    Completed PHASE1_PHASE2

  2. Jan 2022 — Mar 2022 [monthly]

    Completed PHASE1_PHASE2

  3. Jan 2021 — Jan 2022 [monthly]

    Completed PHASE1_PHASE2

  4. Dec 2018 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  5. Jun 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  6. Oct 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  7. Jun 2017 — Oct 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

May 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Erasmus Medical Center
  • Havenziekenhuis
  • Radboud University Medical Center
  • The PATH Malaria Vaccine Initiative (MVI)
Data source: Radboud University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .