deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03144687

A Study of Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis

An Open-Label Phase 2 Study of Itacitinib (INCB039110) in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Subjects With Myelofibrosis

Sponsor: Incyte Corporation

Updated 16 times since 2017 Last updated: May 17, 2022 Started: Jan 26, 2018 Primary completion: Mar 14, 2020 Completion: Jun 1, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates MPN (Myeloproliferative Neoplasms) and is currently completed. Incyte Corporation leads this study, which shows 16 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2017 – ~Oct 2017 · 3 months · monthly snapshot~Oct 2017 – ~Feb 2018 · 4 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Sep 2019 · 4 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Jun 2020 · 8 months · monthly snapshot~Jun 2020 – ~Oct 2020 · 4 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshot~Sep 2021 – ~Jul 2022 · 10 months · monthly snapshot~Jul 2022 – ~Jul 2024 · 24 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jul 2022 — Jul 2024 [monthly]

    Completed PHASE2

  5. Sep 2021 — Jul 2022 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 11 earlier versions
  1. Feb 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  2. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

  3. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Jun 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Oct 2019 — Jun 2020 [monthly]

    Recruiting PHASE2

  6. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  7. May 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  8. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE2

  9. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  10. Oct 2017 — Feb 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  11. Jul 2017 — Oct 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Incyte Corporation
Data source: Incyte Corporation

For direct contact, visit the study record on ClinicalTrials.gov .