deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT03149679

The p53 Colorectal Cancer Trial

Treatment of Patients With Metastatic Colorectal Cancer Harboring TP53 Mutations With Dose-dense Cyclophosphamide - the p53 Colorectal Cancer Trial

Sponsor: Haukeland University Hospital

Interventions Cyclophosphamide
Updated 11 times since 2017 Last updated: Jan 20, 2021 Started: May 9, 2017 Primary completion: Aug 7, 2020 Completion: Aug 7, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was discontinued after the first pre-planned interim analysis due to insufficient response rates.

This PHASE2 trial investigates Colorectal Cancer Metastatic and Colorectal Cancer Stage IV and is currently terminated or withdrawn. Haukeland University Hospital leads this study, which shows 11 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshotNot Yet Recruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotRecruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotRecruiting~Sep 2018 – ~Mar 2020 · 18 months · monthly snapshotRecruiting~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshotRecruiting~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotActive Not Recruiting~Feb 2021 – ~Dec 2021 · 10 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Feb 2021 — Dec 2021 [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  5. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

Show 6 earlier versions
  1. Jun 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Mar 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  3. Sep 2018 — Mar 2020 [monthly]

    Recruiting PHASE2

  4. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  5. Aug 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Jun 2017 — Aug 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

May 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Haukeland University Hospital
Data source: Haukeland University Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations