deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT03150004

Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients with Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

A Phase II Study of the Efficacy and Pharmacogenomics of Cladribine-based Salvage Chemotherapy in Patients with Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

Sponsor: Medical College of Wisconsin

Updated 14 times since 2017 Last updated: Mar 23, 2025 Started: Jun 14, 2017 Primary completion: Mar 14, 2025 Completion: Mar 14, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

No longer have funding support to complete the pharmacogenetics component.

A PHASE2 clinical study on Acute Myeloid Leukemia and Myelodysplastic Syndrome, this trial is terminated or withdrawn. The trial is conducted by Medical College of Wisconsin and has accumulated 14 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2017 – ~Sep 2017 · 3 months · monthly snapshot~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Apr 2019 · 8 months · monthly snapshot~Apr 2019 – ~Apr 2020 · 12 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~May 2022 · 12 months · monthly snapshot~May 2022 – ~May 2023 · 12 months · monthly snapshot~May 2023 – ~May 2024 · 12 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – present · 15 months · monthly snapshot

Change History

14 versions recorded
  1. Apr 2025 — Present [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  2. Sep 2024 — Apr 2025 [monthly]

    Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  5. May 2023 — May 2024 [monthly]

    Recruiting PHASE2

Show 9 earlier versions
  1. May 2022 — May 2023 [monthly]

    Recruiting PHASE2

  2. May 2021 — May 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  4. Apr 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Apr 2019 — Apr 2020 [monthly]

    Recruiting PHASE2

  6. Aug 2018 — Apr 2019 [monthly]

    Recruiting PHASE2

  7. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  8. Sep 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  9. Jun 2017 — Sep 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Medical College of Wisconsin
Data source: Medical College of Wisconsin

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations