deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT03154333

Safety and Efficacy of Diacerein 1% Ointment for Subjects With Epidermolysis Bullosa Simplex (EBS)

An International, Multicenter, Randomized, Double-Blind, Parallel-Group Phase 2 Study Evaluating the Safety and Efficacy of Diacerein 1% Ointment Topical Formulation in Subjects With Epidermolysis Bullosa Simplex

Sponsor: Castle Creek Pharmaceuticals, LLC

Updated 18 times since 2017 Last updated: Oct 16, 2019 Started: Jun 1, 2017 Primary completion: Oct 15, 2018 Completion: Oct 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Futility

A PHASE2 clinical study on Epidermolysis Bullosa Simplex, this trial is terminated or withdrawn. The trial is conducted by Castle Creek Pharmaceuticals, LLC and has accumulated 18 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Sep 2017 · 2 months · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Jan 2018 · 3 months · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Dec 2019 · 13 months · monthly snapshot~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshot~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

18 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE2

Show 13 earlier versions
  1. Jan 2021 — Dec 2022 [monthly]

    Terminated PHASE2

  2. Dec 2019 — Jan 2021 [monthly]

    Terminated PHASE2

  3. Nov 2018 — Dec 2019 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  4. Aug 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  5. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  6. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  7. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  8. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE2

  9. Jan 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  10. Oct 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  11. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  12. Jul 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

  13. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Castle Creek Pharmaceuticals, LLC
Data source: Castle Creek Pharmaceuticals, LLC

For direct contact, visit the study record on ClinicalTrials.gov .