deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT03157167

An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)

An Evaluation of the Safety of Escalating Doses of Tc 99m Tilmanocept by Intravenous (IV) Injection and a Comparison to Subcutaneous (SC) Injection in Human Immunodeficiency Virus (HIV) Subjects Diagnosed With Kaposi Sarcoma (KS)

Sponsor: National Cancer Institute (NCI)

Interventions Tc99m-tilmanocept
Updated 12 times since 2017 Last updated: Feb 12, 2025 Started: Dec 1, 2017 Primary completion: Nov 5, 2019 Completion: Mar 30, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates HIV Infections and Kaposi Sarcoma and is currently completed. National Cancer Institute (NCI) leads this study, which shows 12 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshotNot Yet Recruiting~Aug 2017 – ~Dec 2017 · 4 months · monthly snapshotNot Yet Recruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotRecruiting~Sep 2018 – ~Apr 2019 · 7 months · monthly snapshotRecruiting~Apr 2019 – ~Apr 2020 · 12 months · monthly snapshotRecruiting~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshotActive Not Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotCompleted~Apr 2025 – present · 15 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Apr 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Apr 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Aug 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 7 earlier versions
  1. Apr 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Apr 2019 — Apr 2020 [monthly]

    Recruiting PHASE1

  3. Sep 2018 — Apr 2019 [monthly]

    Recruiting PHASE1

    Phase: EARLY_PHASE1PHASE1

  4. Jun 2018 — Sep 2018 [monthly]

    Recruiting EARLY_PHASE1

  5. Dec 2017 — Jun 2018 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet RecruitingRecruiting

  6. Aug 2017 — Dec 2017 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  7. Jun 2017 — Aug 2017 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • National Institutes of Health (NIH)
  • Navidea Biopharmaceuticals
Data source: Navidea Biopharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations