deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT03172975

Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection

Phase 2 Study to Assess the Safety, Efficacy and Immunogenicity of Na-GST-1/Alhydrogel Co-administered With Different Toll-Like Receptor Agonists in Hookworm- Naïve Adults

Sponsor: Baylor College of Medicine

Updated 26 times since 2017 Last updated: Feb 27, 2026 Started: Mar 1, 2018 Primary completion: Dec 31, 2024 Completion: Jan 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Hookworm Infections, this trial is completed. The trial is conducted by Baylor College of Medicine and has accumulated 26 data snapshots since 2018. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jun 2017 – ~Mar 2018 · 9 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Aug 2019 · 12 months · monthly snapshot~Aug 2019 – ~Feb 2020 · 6 months · monthly snapshot~Feb 2020 – ~Aug 2020 · 6 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Feb 2024 · 6 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – ~Mar 2026 · 59 days · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

26 versions recorded
  1. Mar 2026 — Present [monthly]

    Completed PHASE2

  2. Jan 2026 — Mar 2026 [monthly]

    Completed PHASE2

  3. Sep 2025 — Jan 2026 [monthly]

    Completed PHASE2

  4. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE2

  5. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE2

Show 21 earlier versions
  1. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE2

  2. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Aug 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

  6. May 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2

  7. Mar 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: CompletedActive Not Recruiting

  8. Feb 2023 — Mar 2023 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  9. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  10. Apr 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  11. Feb 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2

  12. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  13. Apr 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  14. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  15. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  16. Feb 2020 — Aug 2020 [monthly]

    Recruiting PHASE2

  17. Aug 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  18. Aug 2018 — Aug 2019 [monthly]

    Recruiting PHASE2

  19. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  20. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  21. Jun 2017 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Baylor College of Medicine
  • George Washington University
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: Baylor College of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .