deltatrials
Completed PHASE3 INTERVENTIONAL 8-arm NCT03176134

A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)

A Phase III Randomized, Active-comparator-Controlled Clinical Trial to Study the Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator, in Subjects From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (ABSSSI)

Sponsor: Merck Sharp & Dohme LLC

Conditions Acute Bacterial Skin and Skin Structure Infections
Interventions Comparator Tedizolid phosphate
Updated 52 times since 2017 Last updated: Jul 18, 2025 Started: Jan 20, 2019 Primary completion: Jul 6, 2023 Completion: Jul 6, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Acute Bacterial Skin and Skin Structure Infections, this trial is completed. The trial is conducted by Merck Sharp & Dohme LLC and has accumulated 52 data snapshots since 2019. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Aug 2025 · 10 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

52 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Aug 2025 — Sep 2025 [monthly]

    Completed PHASE3

  3. Oct 2024 — Aug 2025 [monthly]

    Completed PHASE3

  4. Sep 2024 — Oct 2024 [monthly]

    Completed PHASE3

  5. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE3

▶ Show 47 earlier versions

  1. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE3

  2. Aug 2023 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  3. Jul 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  4. May 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  5. Mar 2023 — May 2023 [monthly]

    Recruiting PHASE3

  6. Dec 2022 — Mar 2023 [monthly]

    Recruiting PHASE3

  7. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  8. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  9. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  10. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  11. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  12. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  13. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  14. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  15. Oct 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  16. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  17. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  18. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  19. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  20. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  21. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  22. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  23. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  24. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  25. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  26. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  27. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  28. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

    Status: Suspended → Recruiting

  29. Jun 2020 — Jul 2020 [monthly]

    Suspended PHASE3

    Status: Recruiting → Suspended

  30. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  31. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE3

  32. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  33. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  34. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  35. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  36. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  37. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  38. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  39. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  40. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  41. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  42. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  43. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  44. Nov 2018 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE3

  45. Sep 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE3

  46. Jun 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE3

  47. Jul 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adana, Turkey (Türkiye) , Aguascalientes, Mexico , Ankara, Turkey (Türkiye) , Batumi, Georgia , Burgas, Bulgaria , Bydgoszcz, Poland , Chicago, United States , Curitiba, Brazil , Daugavpils, Latvia , Detroit, United States and 37 more locations