deltatrials
Completed EARLY_PHASE1 INTERVENTIONAL 2-arm NCT03182959

Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer

A Phase 0 Study Evaluating the Systemic Bioavailability and Pharmacodynamic Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer

Sponsor: National Cancer Institute (NCI)

Interventions Avmacol®
Updated 10 times since 2017 Last updated: Jun 17, 2021 Started: Apr 24, 2017 Primary completion: Jan 1, 2020 Completion: Jan 19, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A EARLY_PHASE1 clinical study on Carcinoma in Situ and Dysplasia, this trial is completed. The trial is conducted by National Cancer Institute (NCI) and has accumulated 10 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshotNot Yet Recruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshotRecruiting~Dec 2018 – ~Dec 2019 · 12 months · monthly snapshotRecruiting~Dec 2019 – ~Apr 2020 · 4 months · monthly snapshotRecruiting~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotActive Not Recruiting~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed EARLY_PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed EARLY_PHASE1

  3. Sep 2021 — Jul 2024 [monthly]

    Completed EARLY_PHASE1

    Status: Active Not RecruitingCompleted

  4. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting EARLY_PHASE1

  5. Apr 2020 — Jan 2021 [monthly]

    Active Not Recruiting EARLY_PHASE1

    Status: RecruitingActive Not Recruiting

Show 5 earlier versions
  1. Dec 2019 — Apr 2020 [monthly]

    Recruiting EARLY_PHASE1

  2. Dec 2018 — Dec 2019 [monthly]

    Recruiting EARLY_PHASE1

  3. Jun 2018 — Dec 2018 [monthly]

    Recruiting EARLY_PHASE1

  4. Dec 2017 — Jun 2018 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet RecruitingRecruiting

  5. Jun 2017 — Dec 2017 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Apr 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • University of Arizona
Data source: University of Arizona

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations