deltatrials
Terminated NA INTERVENTIONAL 1-arm NCT03202641

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients: an Open Lung is a Better Heart

Sponsor: Massachusetts General Hospital

Conditions ARDS, Human Alveolar Edema Lung Injury, Acute Mechanical Ventilation Complication Respiratory Distress Syndrome Right Heart Failure Right Ventricular Dysfunction
Interventions PEEP ARDSnet PEEP LRM
Updated 14 times since 2017 Last updated: Dec 12, 2025 Started: Jun 19, 2019 Primary completion: May 12, 2020 Completion: May 12, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

COVID pandemic

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Other ARDS, Human trials with similar outcome

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This NA trial investigates ARDS, Human and Alveolar Edema and is currently terminated or withdrawn. Massachusetts General Hospital leads this study, which shows 14 recorded versions since 2019 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jul 2017 – ~Oct 2017 · 3 months · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Dec 2020 · 15 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Dec 2022 · 14 months · monthly snapshot~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Jan 2026 · 13 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

14 versions recorded

  1. Jan 2026 — Present [monthly]

    Terminated NA

    Status: Unknown → Terminated

  2. Dec 2024 — Jan 2026 [monthly]

    Unknown NA

    Status: Recruiting → Unknown

  3. Sep 2024 — Dec 2024 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Dec 2022 — Jul 2024 [monthly]

    Recruiting NA

▶ Show 9 earlier versions

  1. Oct 2021 — Dec 2022 [monthly]

    Recruiting NA

  2. Jan 2021 — Oct 2021 [monthly]

    Recruiting NA

  3. Dec 2020 — Jan 2021 [monthly]

    Recruiting NA

  4. Sep 2019 — Dec 2020 [monthly]

    Recruiting NA

  5. Apr 2019 — Sep 2019 [monthly]

    Recruiting NA

  6. Dec 2018 — Apr 2019 [monthly]

    Recruiting NA

  7. Jun 2018 — Dec 2018 [monthly]

    Recruiting NA

  8. Oct 2017 — Jun 2018 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  9. Jul 2017 — Oct 2017 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Massachusetts General Hospital
Data source: Massachusetts General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations