deltatrials
Completed PHASE3 INTERVENTIONAL 3-arm NCT03204318

SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

SPIRIT 1: An International Phase 3 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study to Evaluate Relugolix Administered With and Without Low-Dose Estradiol and Norethindrone Acetate in Women With Endometriosis-Associated Pain

Sponsor: Myovant Sciences GmbH

Updated 29 times since 2017 Last updated: Jun 25, 2021 Started: Dec 7, 2017 Primary completion: Jun 9, 2020 Completion: Apr 8, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Endometriosis Related Pain and is currently completed. Myovant Sciences GmbH leads this study, which shows 29 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Dec 2018 · 5 months · monthly snapshot~Dec 2018 – ~May 2019 · 5 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Sep 2019 · 3 months · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

29 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Sep 2021 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

Show 24 earlier versions
  1. May 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE3

  2. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  3. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  7. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  8. Aug 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  10. Mar 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  11. Nov 2019 — Mar 2020 [monthly]

    Recruiting PHASE3

  12. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  13. Jun 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  14. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  15. Dec 2018 — May 2019 [monthly]

    Recruiting PHASE3

  16. Jul 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  18. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  19. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE3

  20. Jan 2018 — Feb 2018 [monthly]

    Recruiting PHASE3

  21. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  22. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  23. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  24. Aug 2017 — Oct 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Myovant Sciences GmbH
Data source: Myovant Sciences GmbH

For direct contact, visit the study record on ClinicalTrials.gov .