Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis (MANUS)
Mesenchymal Stromal Cells for Angiogenesis and Neovascularisation in Digital Ulcers of Systemic Sclerosis: the MANUS Trial
Sponsor: UMC Utrecht
Listed as NCT03211793, this PHASE1/PHASE2 trial focuses on Digital Ulcer and Systemic Sclerosis and remains actively recruiting participants. Sponsored by UMC Utrecht, it has been updated 10 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Status Flow
Change History
10 versions recorded-
Oct 2025 — Present [monthly]
Recruiting PHASE1/PHASE2
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Sep 2024 — Oct 2025 [monthly]
Recruiting PHASE1/PHASE2
-
Jul 2024 — Sep 2024 [monthly]
Recruiting PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
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Jan 2024 — Jul 2024 [monthly]
Recruiting PHASE1_PHASE2
-
Apr 2022 — Jan 2024 [monthly]
Recruiting PHASE1_PHASE2
Status: Unknown Status → Recruiting
▶ Show 5 earlier versions
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Jan 2021 — Apr 2022 [monthly]
Unknown Status PHASE1_PHASE2
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Dec 2020 — Jan 2021 [monthly]
Unknown Status PHASE1_PHASE2
Status: Not Yet Recruiting → Unknown Status
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Jul 2018 — Dec 2020 [monthly]
Not Yet Recruiting PHASE1_PHASE2
Status: Recruiting → Not Yet Recruiting
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Jun 2018 — Jul 2018 [monthly]
Recruiting PHASE1_PHASE2
-
Aug 2017 — Jun 2018 [monthly]
Recruiting PHASE1_PHASE2
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- UMC Utrecht
- ZonMw: The Netherlands Organisation for Health Research and Development
For direct contact, visit the study record on ClinicalTrials.gov .