deltatrials
Completed PHASE2 INTERVENTIONAL 8-arm NCT03224351

A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis

A Phase 2, Randomized, Double-blind, Controlled Study to Evaluate the Safety and Efficacy of VX-659 Combination Therapy in Subjects Aged 18 Years and Older With Cystic Fibrosis

Sponsor: Vertex Pharmaceuticals Incorporated

Updated 15 times since 2017 Last updated: Mar 29, 2021 Started: Aug 8, 2017 Primary completion: Feb 28, 2018 Completion: Feb 28, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03224351, this PHASE2 trial focuses on Cystic Fibrosis and remains completed. Sponsored by Vertex Pharmaceuticals Incorporated, it has been updated 15 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jan 2021 · 21 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Dec 2022 · 19 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. May 2021 — Dec 2022 [monthly]

    Completed PHASE2

Show 10 earlier versions
  1. Jan 2021 — May 2021 [monthly]

    Completed PHASE2

  2. Apr 2019 — Jan 2021 [monthly]

    Completed PHASE2

  3. Jun 2018 — Apr 2019 [monthly]

    Completed PHASE2

  4. May 2018 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Mar 2018 — May 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  6. Dec 2017 — Mar 2018 [monthly]

    Recruiting PHASE2

  7. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  8. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE2

  9. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  10. Aug 2017 — Sep 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Vertex Pharmaceuticals Incorporated
Data source: Vertex Pharmaceuticals Incorporated

For direct contact, visit the study record on ClinicalTrials.gov .