deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT03225287

Extension Study of RA101495 for Patients With PNH Who Have Completed a Zilucoplan (RA101495) Clinical Study

A Multicenter, Open-label, Uncontrolled, Extension Study of RA101495 in Subjects With Paroxysmal Nocturnal Hemoglobinuria Who Have Completed a RA101495 Clinical Study

Sponsor: Ra Pharmaceuticals, Inc.

Updated 19 times since 2017 Last updated: Sep 20, 2023 Started: Jul 17, 2017 Primary completion: Sep 7, 2021 Completion: Oct 26, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

After careful consideration, UCB has decided to no longer pursue PNH as a potential indication for zilucoplan.

Other terminated trials from Ra Pharmaceuticals, Inc.

More terminations from Ra Pharmaceuticals, Inc.

Listed as NCT03225287, this PHASE2 trial focuses on Paroxysmal Nocturnal Hemoglobinuria (PNH) and remains terminated or withdrawn. Sponsored by Ra Pharmaceuticals, Inc., it has been updated 19 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2017 – ~Mar 2018 · 7 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2019 · 13 months · monthly snapshot~Jul 2019 – ~Jan 2021 · 18 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Oct 2023 · 11 months · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshot

Change History

19 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Oct 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Nov 2022 — Oct 2023 [monthly]

    Terminated PHASE2

  5. Sep 2022 — Nov 2022 [monthly]

    Terminated PHASE2

Show 14 earlier versions
  1. May 2022 — Sep 2022 [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  2. Apr 2022 — May 2022 [monthly]

    Completed PHASE2

  3. Feb 2022 — Apr 2022 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Dec 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  7. May 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE2

  10. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  11. Jul 2019 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  12. Jun 2018 — Jul 2019 [monthly]

    Active Not Recruiting PHASE2

  13. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  14. Aug 2017 — Mar 2018 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ra Pharmaceuticals, Inc.
Data source: UCB Pharma

For direct contact, visit the study record on ClinicalTrials.gov .