deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 2-arm NCT03229564

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children

A Phase IIb, Prospective, Intra-patient Randomised Controlled, Multicentre Study to Evaluate the Safety and Efficacy of an Autologous Bio-engineered Dermo-epidermal Skin Substitute (EHSG-KF) for the Treatment of Partial Deep Dermal and Full Thickness Burns in Children in Comparison to Autologous Split-thickness Skin Grafts (STSG)

Sponsor: CUTISS AG

Conditions Burns
Interventions EHSG-KF STSG
Updated 20 times since 2017 Last updated: May 19, 2025 Started: Oct 25, 2017 Primary completion: Jun 30, 2026 Completion: Jun 30, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Burns, this trial is ongoing. The trial is conducted by CUTISS AG and has accumulated 20 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Aug 2017 – ~Dec 2017 · 4 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Nov 2019 · 11 months · monthly snapshot~Nov 2019 – ~Aug 2020 · 9 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Oct 2021 · 7 months · monthly snapshot~Oct 2021 – ~Jun 2022 · 8 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshot~Nov 2022 – ~Mar 2023 · 4 months · monthly snapshot~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

20 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Mar 2025 — Jun 2025 [monthly]

    Recruiting PHASE2

  4. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE2

    Phase: PHASE2/PHASE3 → PHASE2

  5. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE2/PHASE3

▶ Show 15 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  2. Mar 2023 — Jul 2024 [monthly]

    Recruiting PHASE2_PHASE3

  3. Nov 2022 — Mar 2023 [monthly]

    Recruiting PHASE2_PHASE3

  4. Jul 2022 — Nov 2022 [monthly]

    Recruiting PHASE2_PHASE3

  5. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2_PHASE3

  6. Oct 2021 — Jun 2022 [monthly]

    Recruiting PHASE2_PHASE3

  7. Mar 2021 — Oct 2021 [monthly]

    Recruiting PHASE2_PHASE3

  8. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE2_PHASE3

  9. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2_PHASE3

  10. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE2_PHASE3

  11. Nov 2019 — Aug 2020 [monthly]

    Recruiting PHASE2_PHASE3

  12. Dec 2018 — Nov 2019 [monthly]

    Recruiting PHASE2_PHASE3

  13. Jun 2018 — Dec 2018 [monthly]

    Recruiting PHASE2_PHASE3

  14. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet Recruiting → Recruiting

  15. Aug 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • CUTISS AG
  • Julius Clinical
  • Sintesi Research Srl
  • University Hospital, Zürich
  • University of Zurich
  • Wyss Zurich
Data source: CUTISS AG

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations