deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT03258658

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

A Phase 1 Pilot Safety and Feasibility Study of Autologous Engineered Urethral

Sponsor: United States Department of Defense

Conditions Male Urogenital Diseases Urethral Injury Urethral Stricture Urologic Diseases
Interventions Autologous Engineered Urethral Construct
Updated 36 times since 2017 Last updated: Aug 26, 2025 Started: Mar 31, 2026 Primary completion: Dec 31, 2028 Completion: Dec 31, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Male Urogenital Diseases and Urethral Injury, this trial is actively recruiting participants. The trial is conducted by United States Department of Defense and has accumulated 36 data snapshots since 2026. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Sep 2017 – ~May 2018 · 8 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~Mar 2019 · 3 months · monthly snapshot~Mar 2019 – ~Nov 2019 · 8 months · monthly snapshot~Nov 2019 – ~Feb 2020 · 3 months · monthly snapshot~Feb 2020 – ~Sep 2020 · 7 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Jan 2023 · 2 months · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Jun 2024 · 6 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

36 versions recorded

  1. Sep 2025 — Present [monthly]

    Recruiting PHASE1

  2. Mar 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  3. Dec 2024 — Mar 2025 [monthly]

    Recruiting PHASE1

  4. Oct 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  5. Sep 2024 — Oct 2024 [monthly]

    Not Yet Recruiting PHASE1

▶ Show 31 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE1

  2. Jun 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE1

  3. Dec 2023 — Jun 2024 [monthly]

    Not Yet Recruiting PHASE1

  4. Oct 2023 — Dec 2023 [monthly]

    Not Yet Recruiting PHASE1

  5. Sep 2023 — Oct 2023 [monthly]

    Not Yet Recruiting PHASE1

  6. Jun 2023 — Sep 2023 [monthly]

    Not Yet Recruiting PHASE1

  7. Mar 2023 — Jun 2023 [monthly]

    Not Yet Recruiting PHASE1

  8. Jan 2023 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE1

  9. Nov 2022 — Jan 2023 [monthly]

    Not Yet Recruiting PHASE1

  10. Sep 2022 — Nov 2022 [monthly]

    Not Yet Recruiting PHASE1

  11. Apr 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE1

  12. Jan 2022 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE1

  13. Dec 2021 — Jan 2022 [monthly]

    Not Yet Recruiting PHASE1

  14. Oct 2021 — Dec 2021 [monthly]

    Not Yet Recruiting PHASE1

  15. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE1

  16. Jun 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1

  17. May 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE1

  18. Apr 2021 — May 2021 [monthly]

    Not Yet Recruiting PHASE1

  19. Mar 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE1

  20. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE1

  21. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

  22. Nov 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE1

    Status: Suspended → Not Yet Recruiting

  23. Sep 2020 — Nov 2020 [monthly]

    Suspended PHASE1

  24. Feb 2020 — Sep 2020 [monthly]

    Suspended PHASE1

  25. Nov 2019 — Feb 2020 [monthly]

    Suspended PHASE1

  26. Mar 2019 — Nov 2019 [monthly]

    Suspended PHASE1

    Status: Not Yet Recruiting → Suspended

  27. Dec 2018 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE1

  28. Sep 2018 — Dec 2018 [monthly]

    Not Yet Recruiting PHASE1

  29. Jun 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE1

  30. May 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1

    Status: Recruiting → Not Yet Recruiting

  31. Sep 2017 — May 2018 [monthly]

    Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • United States Department of Defense
  • Wake Forest University Health Sciences
Data source: Wake Forest University Health Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations