deltatrials
Terminated EARLY_PHASE1 INTERVENTIONAL 2-arm NCT03272633

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Post-Transplant Use of Irradiated Haplo-Allogeneic Cells

Sponsor: National Cancer Institute (NCI)

Conditions Acute Lymphoblastic Leukemia Acute Myeloid Leukemia in Remission Hematopoietic Cell Transplantation Recipient JAK2 Gene Mutation Loss of Chromosome 17p Mantle Cell Lymphoma Minimal Residual Disease Myelodysplastic Syndrome Non-Hodgkin Lymphoma Plasma Cell Myeloma RAS Family Gene Mutation Recurrent Diffuse Large B-Cell Lymphoma Recurrent Hematologic Malignancy Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma TP53 Gene Mutation Therapy-Related Acute Myeloid Leukemia Therapy-Related Myelodysplastic Syndrome
Interventions Allogeneic Hematopoietic Stem Cell Transplantation Irradiated Allogeneic Cells
Updated 21 times since 2017 Last updated: Jun 23, 2023 Started: Oct 26, 2020 Primary completion: Jun 30, 2022 Completion: Sep 22, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of enrollment

Other terminated trials from National Cancer Institute (NCI)

See all terminations from National Cancer Institute (NCI)

Other Acute Lymphoblastic Leukemia trials with similar outcome

Browse all Acute Lymphoblastic Leukemia trials

Listed as NCT03272633, this EARLY_PHASE1 trial focuses on Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia in Remission and remains terminated or withdrawn. Sponsored by National Cancer Institute (NCI), it has been updated 21 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~May 2019 · 4 months · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Jul 2020 · 5 months · monthly snapshot~Jul 2020 – ~Nov 2020 · 4 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Jun 2022 · 9 months · monthly snapshot~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2023 · 6 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

21 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated EARLY_PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated EARLY_PHASE1

  3. Jul 2023 — Jul 2024 [monthly]

    Terminated EARLY_PHASE1

    Status: Active Not Recruiting → Terminated

  4. Jan 2023 — Jul 2023 [monthly]

    Active Not Recruiting EARLY_PHASE1

  5. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting EARLY_PHASE1

    Status: Recruiting → Active Not Recruiting

▶ Show 16 earlier versions

  1. Jun 2022 — Dec 2022 [monthly]

    Recruiting EARLY_PHASE1

  2. Sep 2021 — Jun 2022 [monthly]

    Recruiting EARLY_PHASE1

  3. May 2021 — Sep 2021 [monthly]

    Recruiting EARLY_PHASE1

  4. Jan 2021 — May 2021 [monthly]

    Recruiting EARLY_PHASE1

  5. Dec 2020 — Jan 2021 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet Recruiting → Recruiting

  6. Nov 2020 — Dec 2020 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  7. Jul 2020 — Nov 2020 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  8. Feb 2020 — Jul 2020 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  9. Jan 2020 — Feb 2020 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    Phase: PHASE2 → EARLY_PHASE1

  10. Nov 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE2

  11. Aug 2019 — Nov 2019 [monthly]

    Not Yet Recruiting PHASE2

  12. May 2019 — Aug 2019 [monthly]

    Not Yet Recruiting PHASE2

  13. Jan 2019 — May 2019 [monthly]

    Not Yet Recruiting PHASE2

  14. Nov 2018 — Jan 2019 [monthly]

    Not Yet Recruiting PHASE2

  15. Jun 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE2

  16. Oct 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Rutgers, The State University of New Jersey
Data source: Rutgers, The State University of New Jersey

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations