deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT03292458

Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor

Central Mechanisms and Treatment Response of Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor

Sponsor: Kristina Simonyan

Conditions Spasmodic Dysphonia Voice Tremor
Interventions Sodium Oxybate
Updated 17 times since 2017 Last updated: Dec 9, 2025 Started: Jan 22, 2018 Primary completion: Dec 29, 2021 Completion: Oct 11, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Spasmodic Dysphonia and Voice Tremor and is currently completed. Kristina Simonyan leads this study, which shows 17 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Oct 2017 – ~Jan 2018 · 3 months · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Mar 2020 · 13 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~Nov 2023 · 7 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – ~Jan 2026 · 8 months · monthly snapshot~Jan 2026 – present · 7 months · monthly snapshot

Change History

17 versions recorded

  1. Jan 2026 — Present [monthly]

    Completed PHASE2/PHASE3

  2. May 2025 — Jan 2026 [monthly]

    Completed PHASE2/PHASE3

    Status: Active Not Recruiting → Completed

  3. Sep 2024 — May 2025 [monthly]

    Active Not Recruiting PHASE2/PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  5. Nov 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

▶ Show 12 earlier versions

  1. Apr 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Apr 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  3. Feb 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: Recruiting → Active Not Recruiting

  4. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE2_PHASE3

  5. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE2_PHASE3

  6. Mar 2021 — Jun 2021 [monthly]

    Recruiting PHASE2_PHASE3

  7. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2_PHASE3

  8. Mar 2020 — Jan 2021 [monthly]

    Recruiting PHASE2_PHASE3

  9. Feb 2019 — Mar 2020 [monthly]

    Recruiting PHASE2_PHASE3

  10. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE2_PHASE3

  11. Jan 2018 — Jun 2018 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Active Not Recruiting → Recruiting

  12. Oct 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kristina Simonyan
  • National Institute on Deafness and Other Communication Disorders (NIDCD)
Data source: Massachusetts Eye and Ear Infirmary

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations