deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT03301506

Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

ASSURE: An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects With Primary Biliary Cholangitis (PBC)

Sponsor: Gilead Sciences

Updated 51 times since 2017 Last updated: Dec 19, 2025 Started: Dec 12, 2017 Primary completion: Nov 30, 2028 Completion: Nov 30, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Primary Biliary Cirrhosis and is currently ongoing. Gilead Sciences leads this study, which shows 51 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Nov 2019 · 6 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Nov 2020 · 10 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Jan 2023 · 2 months · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

51 versions recorded
  1. Jan 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  3. May 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Apr 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Mar 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

Show 46 earlier versions
  1. Dec 2024 — Mar 2025 [monthly]

    Recruiting PHASE3

  2. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

  3. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  4. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  6. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  7. Sep 2023 — Mar 2024 [monthly]

    Recruiting PHASE3

  8. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  9. May 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  10. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  11. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  12. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  13. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE3

  14. Nov 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  15. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  16. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  17. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  18. Apr 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  19. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  20. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  21. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  22. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  23. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  24. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  25. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  26. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  27. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  28. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  29. Jan 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE3

  30. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

    Status: SuspendedActive Not Recruiting · Phase: PHASE2_PHASE3PHASE3

  31. Jan 2020 — Nov 2020 [monthly]

    Suspended PHASE2_PHASE3

    Status: RecruitingSuspended

  32. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE2_PHASE3

  33. May 2019 — Nov 2019 [monthly]

    Recruiting PHASE2_PHASE3

  34. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2_PHASE3

  35. Jan 2019 — Apr 2019 [monthly]

    Recruiting PHASE2_PHASE3

  36. Nov 2018 — Jan 2019 [monthly]

    Recruiting PHASE2_PHASE3

  37. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2_PHASE3

  38. Aug 2018 — Oct 2018 [monthly]

    Recruiting PHASE2_PHASE3

  39. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2_PHASE3

  40. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2_PHASE3

  41. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2_PHASE3

  42. Apr 2018 — May 2018 [monthly]

    Recruiting PHASE2_PHASE3

  43. Mar 2018 — Apr 2018 [monthly]

    Recruiting PHASE2_PHASE3

  44. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2_PHASE3

  45. Dec 2017 — Feb 2018 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet RecruitingRecruiting

  46. Oct 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gilead Sciences
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .