deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT03305666

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

A Randomized Clinical Trial of Single Dose Liposomal Bupivacaine Delivered Via VATS Intercostal Nerve Block vs. Continuous Bupivacaine Infusion Delivered Via Indwelling Subscapular Catheter After Surgical Stabilization of Rib Fractures

Sponsor: Denver Health and Hospital Authority

Conditions Anesthesia, Local Chest Injury Trauma Drug Effect Intercostal Rib Local Infiltration Nerve Pain Opioid Dependence Pain; Catheter (Other) Pneumonia Rib Fractures Rib Trauma Surgical Procedure, Unspecified
Interventions Bupivacaine indwelling catheter Liposomal bupivacaine injection
Updated 12 times since 2017 Last updated: Sep 2, 2021 Started: Oct 5, 2017 Primary completion: Jul 20, 2020 Completion: Jan 31, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03305666, this PHASE4 trial focuses on Anesthesia, Local and Chest Injury Trauma and remains completed. Sponsored by Denver Health and Hospital Authority, it has been updated 12 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotRecruiting~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotRecruiting~Nov 2018 – ~Jul 2019 · 8 months · monthly snapshotRecruiting~Jul 2019 – ~Sep 2020 · 14 months · monthly snapshotRecruiting~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotActive Not Recruiting~May 2021 – ~Sep 2021 · 4 months · monthly snapshotCompleted~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotCompleted~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshotCompleted~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

12 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE4

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  3. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE4

  4. Oct 2021 — Dec 2021 [monthly]

    Completed PHASE4

  5. Sep 2021 — Oct 2021 [monthly]

    Completed PHASE4

▶ Show 7 earlier versions

  1. May 2021 — Sep 2021 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  2. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE4

  3. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  4. Jul 2019 — Sep 2020 [monthly]

    Recruiting PHASE4

  5. Nov 2018 — Jul 2019 [monthly]

    Recruiting PHASE4

  6. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE4

  7. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Denver Health and Hospital Authority
Data source: Denver Health and Hospital Authority

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations