deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT03323346

Phase II Trial of Disulfiram With Copper in Metastatic Breast Cancer (DISC)

Phase II Open Labeled Trial of Disulfiram With Copper in Metastatic Breast Cancer

Sponsor: The Institute of Molecular and Translational Medicine, Czech Republic

Interventions Disulfiram
Updated 12 times since 2017 Last updated: Jul 16, 2025 Started: Sep 29, 2017 Primary completion: Dec 31, 2025 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Breast Neoplasm Female and Metastatic Breast Cancer and is currently actively recruiting participants. The Institute of Molecular and Translational Medicine, Czech Republic leads this study, which shows 12 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshotRecruiting~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshotRecruiting~Dec 2018 – ~Feb 2020 · 14 months · monthly snapshotRecruiting~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshotRecruiting~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotRecruiting~Jun 2021 – ~Sep 2022 · 15 months · monthly snapshotRecruiting~Sep 2022 – ~Apr 2023 · 7 months · monthly snapshotRecruiting~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotRecruiting~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotRecruiting~Aug 2025 – present · 13 months · monthly snapshotRecruiting

Change History

12 versions recorded
  1. Aug 2025 — Present [monthly]

    Recruiting PHASE2

  2. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE2

  3. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  5. Apr 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

Show 7 earlier versions
  1. Sep 2022 — Apr 2023 [monthly]

    Recruiting PHASE2

  2. Jun 2021 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  4. Feb 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Dec 2018 — Feb 2020 [monthly]

    Recruiting PHASE2

  6. Jun 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  7. Nov 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    First recorded

Sep 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • The Institute of Molecular and Translational Medicine, Czech Republic
  • University Hospital Olomouc
Data source: The Institute of Molecular and Translational Medicine, Czech Republic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations