deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03326752

Phase 1b DV281 With an Anti-PD-1 Inhibitor in NSCLC

Phase 1b Dose Escalation and Dose Expansion Trial of DV281 in Combination With an Approved Anti-PD-1 Inhibitor in Subjects With Advanced Non-Small Cell Lung Cancer

Sponsor: Dynavax Technologies Corporation

Conditions Advanced Non Small Cell Lung Cancer
Interventions Approved Anti-PD-1 Inhibitor Breath Actuated Nebulizer DV281 DV281 (RP2D)
Updated 12 times since 2017 Last updated: Jun 15, 2020 Started: Sep 20, 2017 Primary completion: Sep 19, 2019 Completion: Sep 19, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Advanced Non Small Cell Lung Cancer, this trial is completed. The trial is conducted by Dynavax Technologies Corporation and has accumulated 12 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshotRecruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotRecruiting~Nov 2018 – ~Mar 2019 · 4 months · monthly snapshotRecruiting~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshotRecruiting~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshotRecruiting~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshotActive Not Recruiting~Feb 2020 – ~Jul 2020 · 5 months · monthly snapshotActive Not Recruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

12 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jul 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  5. Feb 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

▶ Show 7 earlier versions

  1. Jul 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  2. Apr 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  3. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  4. Nov 2018 — Mar 2019 [monthly]

    Recruiting PHASE1

  5. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  6. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

  7. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE1

    First recorded

Sep 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Dynavax Technologies Corporation
Data source: Dynavax Technologies Corporation

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations