deltatrials
Active Not Recruiting OBSERVATIONAL NCT03349385

Registry of Secondary Revascularization (REVASEC)

Multicenter Registry of Secondary Revascularization

Sponsor: Hospital San Carlos, Madrid

Updated 14 times since 2017 Last updated: Apr 23, 2025 Started: Nov 22, 2017 Primary completion: May 31, 2021 Completion: Dec 15, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03349385, this observational or N/A phase trial focuses on Coronary Arteriosclerosis and Coronary Artery Disease Progression and remains ongoing. Sponsored by Hospital San Carlos, Madrid, it has been updated 14 times since 2017, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Study Description(click to expand)

Secondary or repeated revascularization refers to any repeated coronary intervention following an index coronary revascularization procedure, and represents a wide proportion of patients received in catheterization laboratories. These patients have an increased complexity and worse outcomes than patients without previous revascularization. Clinical investigation has focused in lesion-specific treatments when a single previous revascularization fails, but there is paucity of patient-level information including complex patients with multiple revascularizations. Other gaps in evidence addressed by this study are the absence of a a prognosis-oriented classification of previously revascularized patients and a clinical meaningful definition of revascularization failure. The registry as well intends to provide insights on how secondary revascularization decisions are taken and long term prognosis after secondary revascularization. The registry of secondary revascularization (in Spanish: Registro multicéntrico de reVAscularización SECundaria, REVASEC) is a multicenter, prospective, observational cohort study that incudes consecutive patients with at least one previous coronary revascularization undergoing a clinically indicated diagnostic coronary angiography, in different Spanish hospitals. The aims are describing the incidence, clinical profile, therapeutic management and prognosis of these patients.

Secondary or repeated revascularization refers to any repeated coronary intervention following an index coronary revascularization procedure, and represents a wide proportion of patients received in catheterization laboratories. These patients have an increased complexity and worse outcomes than patients without previous revascularization. Clinical investigation has focused in lesion-specific treatments when a single previous revascularization fails, but there is paucity of patient-level information including complex patients with multiple revascularizations. Other gaps in evidence addressed by this study are the absence of a a prognosis-oriented classification of previously revascularized patients and a clinical meaningful definition of revascularization failure. The registry as well intends to provide insights on how secondary revascularization decisions are taken and long term prognosis after secondary revascularization.

The registry of secondary revascularization (in Spanish: Registro multicéntrico de reVAscularización SECundaria, REVASEC) is a multicenter, prospective, observational cohort study that incudes consecutive patients with at least one previous coronary revascularization undergoing a clinically indicated diagnostic coronary angiography, in different Spanish hospitals. The aims are describing the incidence, clinical profile, therapeutic management and prognosis of these patients.

Status Flow

~Dec 2017 – ~Apr 2018 · 4 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Mar 2019 · 9 months · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Feb 2020 · 9 months · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Oct 2021 · 4 months · monthly snapshot~Oct 2021 – ~Dec 2023 · 26 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – present · 11 months · monthly snapshot~Jan 2026 – present · 3 months · monthly snapshot

Change History

14 versions recorded
  1. Jan 2026 — Present [monthly]

    Active Not Recruiting

  2. May 2025 — Present [monthly]

    Active Not Recruiting

  3. Sep 2024 — May 2025 [monthly]

    Active Not Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

  5. Dec 2023 — Jul 2024 [monthly]

    Active Not Recruiting

Show 9 earlier versions
  1. Oct 2021 — Dec 2023 [monthly]

    Active Not Recruiting

  2. Jun 2021 — Oct 2021 [monthly]

    Active Not Recruiting

  3. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting

  4. Feb 2020 — Jan 2021 [monthly]

    Active Not Recruiting

    Status: RecruitingActive Not Recruiting

  5. May 2019 — Feb 2020 [monthly]

    Recruiting

  6. Mar 2019 — May 2019 [monthly]

    Recruiting

  7. Jun 2018 — Mar 2019 [monthly]

    Recruiting

  8. Apr 2018 — Jun 2018 [monthly]

    Recruiting

    Phase: NANone

  9. Dec 2017 — Apr 2018 [monthly]

    Recruiting NA

    First recorded

Nov 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hospital San Carlos, Madrid
  • Laboratorios Farmacéuticos Rovi, S.A.
  • S&H MEDICAL SCIENCE SERVICE, S.L.
Data source: Hospital San Carlos, Madrid

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations