deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 4-arm NCT03355469

Exercise Dose and Metformin for Vascular Health in Metabolic Syndrome

Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Updated 11 times since 2017 Last updated: Sep 18, 2025 Started: Aug 7, 2017 Primary completion: Mar 11, 2024 Completion: May 23, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03355469, this PHASE2/PHASE3 trial focuses on Metabolic Syndrome and remains completed. Sponsored by National Heart, Lung, and Blood Institute (NHLBI), it has been updated 11 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshotRecruiting~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotRecruiting~Feb 2021 – ~Jan 2023 · 23 months · monthly snapshotActive Not Recruiting~Jan 2023 – ~May 2023 · 4 months · monthly snapshotActive Not Recruiting~May 2023 – ~Jul 2024 · 14 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotCompleted~Apr 2025 – ~Oct 2025 · 6 months · monthly snapshotCompleted~Oct 2025 – present · 9 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Oct 2025 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Apr 2025 — Oct 2025 [monthly]

    Completed PHASE2/PHASE3

  3. Sep 2024 — Apr 2025 [monthly]

    Completed PHASE2/PHASE3

    Status: RecruitingCompleted

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  5. May 2023 — Jul 2024 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Active Not RecruitingRecruiting

Show 6 earlier versions
  1. Jan 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Phase: PHASE4PHASE2_PHASE3

  2. Feb 2021 — Jan 2023 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  3. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE4

  4. Feb 2019 — Jan 2021 [monthly]

    Recruiting PHASE4

  5. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE4

  6. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

    First recorded

Aug 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Heart, Lung, and Blood Institute (NHLBI)
  • Rutgers University
Data source: Rutgers, The State University of New Jersey

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations