deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03375697

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease

A 2-Part Randomized, Placebo-Controlled, Double-Blind, Single and Multiple Ascending Dose Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease

Sponsor: Janssen Research & Development, LLC

Conditions Alzheimer Disease
Interventions JNJ-63733657 Placebo
Updated 21 times since 2018 Last updated: Apr 25, 2025 Started: Dec 22, 2017 Primary completion: Dec 16, 2019 Completion: Dec 16, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Alzheimer Disease, this trial is completed. The trial is conducted by Janssen Research & Development, LLC and has accumulated 21 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Feb 2022 · 13 months · monthly snapshot~Feb 2022 – ~Jan 2023 · 11 months · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – present · 16 months · monthly snapshot

Change History

21 versions recorded

  1. May 2025 — Present [monthly]

    Completed PHASE1

  2. Mar 2025 — May 2025 [monthly]

    Completed PHASE1

  3. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  5. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE1

▶ Show 16 earlier versions

  1. Feb 2022 — Jan 2023 [monthly]

    Completed PHASE1

  2. Jan 2021 — Feb 2022 [monthly]

    Completed PHASE1

  3. Feb 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  4. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE1

  5. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE1

  6. Sep 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  7. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE1

  8. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  9. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  10. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  11. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1

  12. Nov 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  13. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  14. Jun 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  15. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  16. Jan 2018 — Feb 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Dec 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Research & Development, LLC
Data source: Janssen Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations