deltatrials
Completed PHASE2 INTERVENTIONAL 10-arm NCT03386578

Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum

Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for Primary HIV Prevention During Pregnancy and Postpartum in Adolescents and Young Women and Their Infants

Sponsor: Gilead Sciences

Conditions HIV Infections
Interventions Behavioral HIV risk reduction package Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) Enhanced adherence support
Updated 25 times since 2018 Last updated: Jan 27, 2025 Started: Jul 3, 2018 Primary completion: Oct 25, 2023 Completion: Feb 24, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on HIV Infections, this trial is completed. The trial is conducted by Gilead Sciences and has accumulated 25 data snapshots since 2018. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Jan 2019 · 5 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Feb 2020 · 6 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2022 · 7 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Sep 2023 · 4 months · monthly snapshot~Sep 2023 – ~Jan 2024 · 4 months · monthly snapshot~Jan 2024 – ~Apr 2024 · 3 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

25 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE2

  4. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE2

  5. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE2

▶ Show 20 earlier versions

  1. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  2. Jan 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2

  4. May 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  6. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  7. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  8. Dec 2021 — Jul 2022 [monthly]

    Recruiting PHASE2

  9. Jan 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  10. May 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  11. Feb 2020 — May 2020 [monthly]

    Recruiting PHASE2

  12. Aug 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  13. May 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  14. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2

  15. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  16. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  17. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  18. Aug 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  19. Jun 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE2

  20. Jan 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gilead Sciences
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations