Unknown NA INTERVENTIONAL 2-arm NCT03388359

Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma (ECMA)

Sponsor: Lithuanian University of Health Sciences

Conditions Airway Remodelling Allergic Asthma Extracellular Matrix Alteration

Interventions Airway smooth muscle cells Bronchial challenge with allergen Co-culture formation Dermatophagoides pteronyssinus allergen Dosimeter ProvoX (Ganshorn) Eosinophils Extracellular matrix turnover and deposition assessment Fibroblasts Inhibition of Wnt and Smad signaling pathways

Updated 8 times since 2018 Last updated: Sep 4, 2020 Started: Jun 1, 2017 Primary completion: Nov 10, 2020 Completion: Dec 8, 2020

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Airway Remodelling and Allergic Asthma and is currently ongoing. Lithuanian University of Health Sciences leads this study, which shows 8 recorded versions since 2017 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Sep 2024 — Present [monthly]

Unknown NA
Jul 2024 — Sep 2024 [monthly]

Unknown NA

Status: Unknown Status → Unknown
Nov 2022 — Jul 2024 [monthly]

Unknown Status NA

Status: Recruiting → Unknown Status
Jan 2021 — Nov 2022 [monthly]

Recruiting NA
Oct 2020 — Jan 2021 [monthly]

Recruiting NA

▶ Show 3 earlier versions

Mar 2020 — Oct 2020 [monthly]

Recruiting NA
Jun 2018 — Mar 2020 [monthly]

Recruiting NA
Jan 2018 — Jun 2018 [monthly]

Recruiting NA

First recorded

Jun 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Lithuanian University of Health Sciences
Research Council of Lithuania
University of Groningen

Data source: Lithuanian University of Health Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Kaunas, Lithuania