deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT03395340

Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)

Phase II Study of Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Conditions Graft Versus Host Disease JNS Kinase Topical Administration
Interventions Ruxolitinib 1.5% cream vehicle cream
Updated 34 times since 2018 Last updated: Jun 21, 2022 Started: Nov 19, 2018 Primary completion: Jan 31, 2019 Completion: Jan 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Forced to close study due to poor recruitment (company withdrew drug support).

Other terminated trials from National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

See all terminations from National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

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This PHASE2 trial investigates Graft Versus Host Disease and JNS Kinase and is currently terminated or withdrawn. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) leads this study, which shows 34 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Aug 2019 · 4 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Sep 2020 · 8 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

34 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE2

  5. Sep 2022 — Dec 2022 [monthly]

    Terminated PHASE2

    Status: Completed → Terminated

▶ Show 29 earlier versions

  1. Apr 2022 — Sep 2022 [monthly]

    Completed PHASE2

    Status: Recruiting → Completed

  2. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

  3. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE2

  4. Nov 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  5. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  6. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  7. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  8. Apr 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  9. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  10. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  11. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  12. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  13. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  14. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  15. Jan 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

  16. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

  17. Oct 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  18. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  19. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  20. Apr 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  21. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  22. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

  23. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  24. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  25. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  26. Aug 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE2

  27. Jul 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE2

  28. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE2

  29. Jan 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations