deltatrials
Active Not Recruiting NA INTERVENTIONAL 2-arm NCT03399851

Comparison of Amplatzer Amulet and Watchman Device in Patients Undergoing Left Atrial Appendage Closure. (SWISS-APERO) (SWISS-APERO)

Comparison of Amplatzer Amulet vs Watchman Device in Patients Undergoing Left Atrial Appendage Closure: the SWISS-APERO Randomized Clinical Trial

Sponsor: Insel Gruppe AG, University Hospital Bern

Conditions Left Atrial Appendage Closure
Interventions Amplatzer Amulet for left atrial appendage closure Watchman/FLX for left atrial appendage closure
Updated 15 times since 2018 Last updated: May 22, 2024 Started: Jun 19, 2018 Primary completion: Jul 9, 2021 Completion: May 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03399851, this NA trial focuses on Left Atrial Appendage Closure and remains ongoing. Sponsored by Insel Gruppe AG, University Hospital Bern, it has been updated 15 times since 2018, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Nov 2019 · 12 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Apr 2022 · 10 months · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~Jul 2023 · 3 months · monthly snapshot~Jul 2023 – ~Jun 2024 · 11 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting NA

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

  4. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting NA

  5. Jul 2023 — Jun 2024 [monthly]

    Active Not Recruiting NA

▶ Show 10 earlier versions

  1. Apr 2023 — Jul 2023 [monthly]

    Active Not Recruiting NA

  2. Apr 2022 — Apr 2023 [monthly]

    Active Not Recruiting NA

    Phase: PHASE4 → NA

  3. Jun 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  4. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE4

  5. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE4

  6. Mar 2020 — Jun 2020 [monthly]

    Recruiting PHASE4

  7. Nov 2019 — Mar 2020 [monthly]

    Recruiting PHASE4

  8. Nov 2018 — Nov 2019 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  9. Jun 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE4

  10. Feb 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Insel Gruppe AG, University Hospital Bern
Data source: Insel Gruppe AG, University Hospital Bern

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations