deltatrials
Unknown OBSERVATIONAL NCT03401957

The Emergence of RAS Mutations in Metastatic Colorectal Cancer Patients Receiving Cetuximab Treatment

A Non-interventional Uncontrolled Multicenter Study to Investigate the Emergence of RAS Resistance Mutations in RAS Wild Type mCRC Patients Receiving First Line Cetuximab Treatment

Sponsor: Cathay General Hospital

Conditions Colorectal Cancer Drug Resistance Mass Spectrometry RAS-RAF Pathway Deregulation
Interventions Cetuximab liquid biopsy
Updated 8 times since 2018 Last updated: Jan 10, 2018 Started: Jan 31, 2018 Primary completion: Jan 31, 2022 Completion: Jan 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03401957, this observational or N/A phase trial focuses on Colorectal Cancer and Drug Resistance and remains ongoing. Sponsored by Cathay General Hospital, it has been updated 8 times since 2018, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Feb 2018 – ~Apr 2018 · 59 days · monthly snapshotRecruiting~Apr 2018 – ~Jan 2021 · 33 months · monthly snapshotRecruiting~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotRecruiting~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshotUnknown~Dec 2025 – present · 9 months · monthly snapshotUnknown

Change History

8 versions recorded

  1. Dec 2025 — Present [monthly]

    Unknown

  2. Sep 2025 — Dec 2025 [monthly]

    Unknown

  3. Sep 2024 — Sep 2025 [monthly]

    Unknown

  4. Jul 2024 — Sep 2024 [monthly]

    Unknown

    Status: Unknown Status → Unknown

  5. Mar 2022 — Jul 2024 [monthly]

    Unknown Status

    Status: Recruiting → Unknown Status

▶ Show 3 earlier versions

  1. Jan 2021 — Mar 2022 [monthly]

    Recruiting

  2. Apr 2018 — Jan 2021 [monthly]

    Recruiting

    Phase: NA → None

  3. Feb 2018 — Apr 2018 [monthly]

    Recruiting NA

    First recorded

Jan 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cathay General Hospital
  • Kaohsiung Medical University Chung-Ho Memorial Hospital
  • National Cheng-Kung University Hospital
  • National Health Research Institutes, Taiwan
  • Taipei Veterans General Hospital, Taiwan
Data source: National Health Research Institutes, Taiwan

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations