deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03406078

Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma (SOURCE)

A Multicentre, Randomized, Double-Blind, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma (SOURCE)

Sponsor: Amgen

Conditions Asthma
Interventions Placebo Tezepelumab
Updated 35 times since 2018 Last updated: Nov 10, 2021 Started: Mar 5, 2018 Primary completion: Sep 25, 2020 Completion: Sep 25, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Asthma, this trial is completed. The trial is conducted by Amgen and has accumulated 35 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshot~Jan 2022 – ~Jul 2024 · 30 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

35 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Sep 2021 — Jan 2022 [monthly]

    Completed PHASE3

▶ Show 30 earlier versions

  1. Jan 2021 — Sep 2021 [monthly]

    Completed PHASE3

  2. Nov 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  3. Sep 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  5. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

  6. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  7. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE3

  8. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  10. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE3

  11. Nov 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  12. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  13. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  14. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  15. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  16. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  17. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  18. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  19. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  20. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  21. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  22. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  23. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  24. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  25. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  26. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  27. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  28. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  29. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  30. Feb 2018 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adana, Turkey (Türkiye) , Altoona, United States , Anderson, United States , Ankara, Turkey (Türkiye) , Ann Arbor, United States , Aschaffenburg, Germany , Bakersfield, United States , Bamberg, Germany , Berlin, Germany , Buenos Aires, Argentina and 40 more locations