deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03417102

A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors (ATLAS-INH)

ATLAS-INH: A Phase 3 Study to Evaluate the Efficacy and Safety of Fitusiran in Patients With Hemophilia A or B, With Inhibitory Antibodies to Factor VIII or IX

Sponsor: Genzyme, a Sanofi Company

Updated 20 times since 2018 Last updated: Mar 15, 2022 Started: Feb 14, 2018 Primary completion: Nov 25, 2020 Completion: Jun 23, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Hemophilia A and Hemophilia B and is currently completed. Genzyme, a Sanofi Company leads this study, which shows 20 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshot~Feb 2019 – ~Jun 2019 · 4 months · monthly snapshot~Jun 2019 – ~Feb 2020 · 8 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

20 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2022 — Apr 2022 [monthly]

    Completed PHASE3

Show 15 earlier versions
  1. Sep 2021 — Jan 2022 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  3. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  5. Apr 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  7. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  8. Jun 2019 — Feb 2020 [monthly]

    Recruiting PHASE3

  9. Feb 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  10. Sep 2018 — Feb 2019 [monthly]

    Recruiting PHASE3

  11. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  12. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  13. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  14. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE3

  15. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Genzyme, a Sanofi Company
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .