deltatrials
Recruiting NA INTERVENTIONAL 1-arm NCT03422302

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Measuring the Effectiveness of a Continuous Positive Airway Pressure (CPAP) Device to Reduce Tumor Motion and Increase Lung Volume Expansion in Patients Undergoing Stereotactic Body Radiotherapy (SBRT) for Tumors That Move With Respiration

Sponsor: M.D. Anderson Cancer Center

Conditions Lung Carcinoma Malignant Respiratory Tract Neoplasm Metastatic Malignant Neoplasm in the Lung
Interventions Biphasic Positive Airway Pressure Computed Tomography Continuous Positive Airway Pressure Deep Inspiration Breath Hold Radiation Therapy Treatment Planning and Simulation Stereotactic Body Radiation Therapy
Updated 17 times since 2018 Last updated: Jan 23, 2026 Started: Mar 16, 2018 Primary completion: May 31, 2028 Completion: May 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Lung Carcinoma and Malignant Respiratory Tract Neoplasm, this trial is actively recruiting participants. The trial is conducted by M.D. Anderson Cancer Center and has accumulated 17 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Feb 2020 · 6 months · monthly snapshot~Feb 2020 – ~Sep 2020 · 7 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshot~Sep 2022 – ~Jul 2023 · 10 months · monthly snapshot~Jul 2023 – ~Jan 2024 · 6 months · monthly snapshot~Jan 2024 – ~May 2024 · 4 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

17 versions recorded

  1. Feb 2026 — Present [monthly]

    Recruiting NA

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting NA

    Status: Active Not Recruiting → Recruiting · Phase: PHASE1/PHASE2 → NA

  3. Feb 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  4. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

▶ Show 12 earlier versions

  1. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Jan 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Jul 2023 — Jan 2024 [monthly]

    Recruiting PHASE1_PHASE2

  4. Sep 2022 — Jul 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jan 2021 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Sep 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Feb 2020 — Sep 2020 [monthly]

    Recruiting PHASE1_PHASE2

  8. Aug 2019 — Feb 2020 [monthly]

    Recruiting PHASE1_PHASE2

  9. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE1_PHASE2

  10. Jun 2018 — Jun 2019 [monthly]

    Recruiting PHASE1_PHASE2

  11. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet Recruiting → Recruiting

  12. Mar 2018 — Apr 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • M.D. Anderson Cancer Center
  • National Cancer Institute (NCI)
Data source: M.D. Anderson Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations